Detalhe da pesquisa
1.
Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.
Proc Natl Acad Sci U S A
; 120(28): e2219543120, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406092
2.
Neutral sphingomyelinase 2 is required for HIV-1 maturation.
Proc Natl Acad Sci U S A
; 120(28): e2219475120, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406093
3.
Neuronal deletion of nSMase2 reduces the production of Aß and directly protects neurons.
Neurobiol Dis
; 177: 105987, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603748
4.
Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV.
Neurobiol Dis
; 169: 105734, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35462006
5.
Fibroblast growth factor-21 improves insulin action in nonlactating ewes.
Am J Physiol Regul Integr Comp Physiol
; 322(3): R170-R180, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35018810
6.
White Matter Injury Is Associated with Reduced Manual Dexterity and Elevated Serum Ceramides in Subjects with Cerebral Small Vessel Disease.
Cerebrovasc Dis
; 50(1): 100-107, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33279889
7.
Stimulus-dependent modifications in astrocyte-derived extracellular vesicle cargo regulate neuronal excitability.
Glia
; 68(1): 128-144, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31469478
8.
Monocarboxylate transporter 1 in Schwann cells contributes to maintenance of sensory nerve myelination during aging.
Glia
; 68(1): 161-177, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31453649
9.
HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via ß-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.
Am J Pathol
; 187(1): 91-109, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27993242
10.
Intravenous Triacylglycerol Infusion Promotes Ceramide Accumulation and Hepatic Steatosis in Dairy Cows.
J Nutr
; 148(10): 1529-1535, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30281114
11.
Activation of TRPML1 clears intraneuronal Aß in preclinical models of HIV infection.
J Neurosci
; 34(34): 11485-503, 2014 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25143627
12.
Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics.
Brain
; 137(Pt 8): 2271-86, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24893707
13.
Ceramide metabolism analysis in a model of binge drinking reveals both neuroprotective and toxic effects of ethanol.
J Neurochem
; 131(5): 645-54, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25060779
14.
Quantitative detection of free 24S-hydroxycholesterol, and 27-hydroxycholesterol from human serum.
BMC Neurosci
; 15: 137, 2014 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25539717
15.
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
J Extracell Vesicles
; 13(2): e12404, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326288
16.
Deficiency of a Niemann-Pick, type C1-related protein in toxoplasma is associated with multiple lipidoses and increased pathogenicity.
PLoS Pathog
; 7(12): e1002410, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22174676
17.
Internal grant review to increase grant funding for junior investigators.
Ann Neurol
; 82(4): 497-502, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28869672
18.
Ceramides predict verbal memory performance in coronary artery disease patients undertaking exercise: a prospective cohort pilot study.
BMC Geriatr
; 13: 135, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24330446
19.
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer's disease.
Res Sq
; 2023 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37502930
20.
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer's disease mouse model.
Transl Neurodegener
; 12(1): 56, 2023 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38049923